The grid below highlights some of the projects and topics for which Newton partner country researchers are currently seeking a UK collaborator or a UK host institution for British Council calls, and for the NERC Latin America Biodiversity call. It is possible to sort entries alphabetically by "Research area"; "Partner country"; "Partner institution" and "Call". To request further information about any of the projects and their lead applicants, please contact us at firstname.lastname@example.org specifying which project you are interested in, and we will provide you with further details.
IL= Institutional LinksRL= Researcher Links (Workshops or Travel Grants)PhD supervision (Full or Placement) = PhD programmeNERC LatAm = NERC Latin America Biodiversity programme
Trophic ecology of top predators in marine ecosystems and integral approach to the aspects of their complex life cycles that include extensive migrations, such as distribution at sea and diving behavior, their relationship with environmental variables, trophic aspects from the study of the natural abundance of stable isotopes of C and N in predator and potential prey tissues
Novel cell penetrating peptides from marine sources - the application of cell penetrating peptides (CPPs) as antimicrobial peptides (AMPs) for tuberculosis therapeutics
Metastasis, Metabolomics, Expression profiling
Primary breast tumors and the detection of EMT related prognosis poor gene signatures through expression profiling that could help in identifying high risk patients for metastasis and in better clinical management of the disease.
Rice, Wild Oryza species, Introgression, O. sativa complex
Wild Oryza species found to have so many desirable genes for yield and stress tolerance which can be utilized for further improvement. These wild species especially those belong to O. sativa complex are crossable with the cultivated rice which helps to broaden the genetic base of cultivated species.
Perfusion MRI, DCE-MRI, Quantitative MRI
Innovative clinical applications using newly developed post-processing techniques for MR data sets. Developing MR image-processing based clinical application solutions, developing competency in the area of MR Methods/Pulse sequences based data acquisition, MR reconstruction and start contributing to related projects are important priority areas
Drosophila,male fertility, estrogen related receptor, mitochondria
Increasing incidence of male infertility and contribution of environmental chemicals to the same through disruption of endocrine function has become a ongoing global health problem. Accordingly, hormone receptors and their interaction with xenobiotics form the essential component of male reproductive toxicity.
Type 2 Diabetes Mellitus, Gene polymorphism, TCF7L2, KCNJ11, ENPP-1
Once a specific polymorphism is associated with the T2DM, it is marked by naming the gene in closest proximity to it. However, this does not necessarily mean that the variant in question is the molecular defect responsible for the phenotype, nor does it implicate the nearest gene. A goal of this research is to assess the rules for classifying the case (T2DM) and control (non-T2DM) groups along with considering the potential gene-gene (SNP-SNP) interactions. Interest is specially focused on the SNPs that can detect the putative effects of genetic interactions.
Humid temperate forest, remote sensing, low-cost wireless sensor networks, citizen science
Biodiversity conservation and adaptive management in a context of climate and social change
Phytochemicals, Anticancer assays, Tumor biology, Metastasis
I am presently working on the anticancer effect of different varieties of Indian Honey in colon cancer model. I got the initial results based on the MTT assay, DAPI staining, AO/EB staining and Clonogenic assay for the effect of the samples in HCT-116 cell lines. However, the samples are less toxic to the normal cell lines i.e HEK293 cell lines. Now I want to prove the mechanism of action of the same with special reference to EMT
Plant, PGPR, Interaction, Metabolomics, Mechanism
Unravelling the mechanism(s) of Host-PGPR signalling under abiotic stress
Rice, gene cloning, activation tagging, abiotic stress
Characterization of genes identified through activation tagging in Oryza sativa ssp. indica cv. Samba Mahsuri for abiotic stress tolerance - gene cloning, characterizing and raising transgenic varieties of rice by manipulating genes (helicase genes i.e SEN1 and XPB2) identified in activation tagged gain-of-function mutants of rice when screened for high water use efficiency, and responsible for agronomically important traits (particularly stress tolerant varieties).
Forests, Energy , Climate Change, Resilience to natural disasters
Evaluation of mechanical properties in extreme conditions of temperature and atmosphere of five types of wood most used in the construction industry in Peru. Expanding the knowledge about the effect of climate change on forest biodiversity in Peru.
Intrinsically Disordered Proteins (IDPs), Protein Biophysics, Virology
Determine the what role Intrinsically disordered protein play in functionality of Virus, this will help to correlate the Molecular Recognition features (A region of IDPs) and signalling Cascade of Virus and furthur help in exploring the novel drug site and discoveries
Metal oxide nanomaterials, bimetallic alloy nanoparticles, Sensing,
SIZE AND SHAPE
CONTROLLED SYNTHESIS OF METAL OXIDE NANOPARTICLES (MONPs) AND THEIR
i. To identify environmentally benign additives that has better control over size and shape of metal oxide nanoparticles.ii. Design a methodology by which a diverse range of metal oxide NPs such as ZrO2, SnO2, MgO, SiO2 can be synthesized using the identified additives.iii. To tune the size and shape of metal oxide nanoparticles.iv. To characterize the synthesized metal oxide nanoparticles by different microscopic, spectroscopic and diffractometric techniques.v. To study the photocatalytic and sensing activities of these metal oxide nanoparticles.
Crystallography, Structural Biology, Parasitology
Structural and Functional Characterization of Myosin motor domain and its regulatory protein from Entamoeba histolytica. Present research work focused on structural studies of only unconventional myosin IB present in Entamoeba histolytica causing amebiasis. Nearly 50 million people worldwide are infected with this pathogen, causing large-scale morbidity and mortality, particularly in developing countries such as India.
Antimicrobials, Peptide Chemistry, Histidine modification, C-H/N-H activation
Synthesis and application of ring-modified histidines in the identification of potential antimicrobial peptides. Histidine derivatives can be modified in such a way that its analogues would possess dual character i.e. both cationic as well as hydrophobic, due to which, they acquire a wide range of biological activity. Substitution at C-2, C-5 and N-1 positions with various alkyl, aryl and halogen groups has been done so far on the imidazole ring of histidine.